College football odds, picks, lines for Week 10: Proven computer model loving Wake Forest and Kentucky

There are several high-profile games on the Week 10 college football schedule, and the College Football Playoff will continue to take shape as scores come in. The latest Week 10 college football odds list top-raked Alabama as a 14-point favorite over No. 4 LSU at Tiger Stadium. In Ann Arbor, No. 5 Michigan is a 12-point favorite over No. 14 Penn State after the line opened at 10.5. In Lexington, No. 6 Georgia is an 8.5-point favorite over No.11 Kentucky, while in Austin, No. 15 Texas is a two-point favorite over No. 12 West Virginia after that line opened at 2.5. Since this week will define seasons for several teams and college football odds have been on the move, you’ll definitely want to see the latest Week 10 college football picks and predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times, and those who have followed it have seen massive returns. Over the past three years, this proprietary computer model has generated a jaw-dropping $4,210 profit for $100 bettors on its top-rated point-spread picks. 

The model made some huge calls in Week 9, including nailing Oklahoma State’s outright upset of No. 6 Texas. It also was all over Georgia (-6.5) covering against Florida and recommended California (+12) against Washington, as well as Kentucky (+7) against Missouri. Anyone who has followed it is way up. 

Now it has simulated every single play of Week 10 and its college football picks are in. One of the Week 10 college football picks the model is recommending: No. 11 Kentucky covers as an 8.5-point home underdog against No. 6 Georgia. 

There’s a lot riding on this matchup, with the winner clinching the SEC East. The model is calling for Georgia to get the victory, but with a spread approaching double-digits, there’s significant value on the Wildcats in what should be a tight battle.

Kentucky’s defense has been its strength this season, coming into Saturday ranked second in the conference. It held a normally high-powered Missouri offense to just 14 points last week, and the model says the Wildcats will limit Georgia’s vaunted rushing attack to around 150 yards Saturday, helping the Wildcats cover in 54 percent of simulations . 

Another one of the top Week 10 college football picks the model loves: Wake Forest covers at home as six-point underdogs to No. 22 Syracuse. In fact, the model says the Demon Deacons win outright, 37-35, pulling off a major upset.

Syracuse’s two losses came by a combined 11 points this season and they took Clemson to the brink on the road this year. After back-to-back shootout wins over North Carolina and North Carolina State at home, they’ve finally cracked the top 25, but now the model says they’re being overvalued.

Against Wake Forest, Syracuse will have to travel to North Carolina. According to the model, that journey will make a major difference, as the Demon Deacons will get at least 50 yards on the ground from Matt Colburn, Cade Carney and Christian Beal.

That effective rushing attack fuels Wake to a cover in nearly 65 percent of the SportsLine Projection Model’s simulations. Wake Forest wins outright in over half of simulations at +210 and there’s added value in backing the Under (77), which hits 60 percent of the time.

The model also has an extremely strong pick for the showdown between No. 1 Alabama and No. 4 LSU, saying one side hits against the spread in almost 60 percent of simulations, and is calling for a Top 25 team to get stunned on the road by a huge underdog in an upset that will shake up conference standings forever. 

So what college football picks can you make with confidence in Week 10? And what contender gets stunned by a huge underdog? Check out the latest Week 10 college football odds below, and then visit SportsLine to see which teams are winning more than 50 percent of simulations, all from a proven computer model that has returned over $4,000 in profit over the past three seasons.

Nebraska at Ohio State (-18.5, 73.5)
Michigan State at Maryland (+2.5, 45)
Texas A&M at Auburn (-3.5, 48.5)
Louisville at Clemson (-38.5, 61)
South Carolina at Ole Miss (PK, 68)
Iowa at Purdue (-2.5, 51)
Georgia at Kentucky (+8.5, 44.5)
Florida State at NC State (-9, 53.5)
West Virginia at Texas (-2, 58)
Tulane at South Florida (-6, 59.5)
Boston College at Virginia Tech (+2, 57)
Penn State at Michigan (-12, 53.5)
Missouri at Florida (-6, 57)
Utah at Arizona State (+7, 56)
Duke at Miami (-9.5, 50.5)
Notre Dame at Northwestern (+10.5, 53.5)
UCLA at Oregon (-10.5, 63)
Louisiana Tech at Mississippi State (-23.5, 48.5)
Oklahoma at Texas Tech (+13.5, 77.5)
Alabama at LSU (+14, 53.5)
Stanford at Washington (-10.5, 45.5)
California at Washington State (-9.5, 50)

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